The most comprehensive and effective post workout formula
Nitrovol ultimate fast & slow lean muscle protein formula.
The all day lean muscle support associated with the regular consumption of fast, medium and slow release proteins are well-documented in scientific research and now Body Science would like to introduce you to the latest product development – NitroVol Lean Muscle. Lean Muscle, as it is nicknamed, is a combination of supplements including creatine, glutamine, carbohydrates and a blend of quality protein sources.
Each ingredient in this lean muscle formula has been carefully selected, based on scientific research, to have specific physiological effects.
Creatine: Creatine is primarily found in skeletal muscle, where it is used to regenerate ATP (Adenosine Triphosphate), an important source of cellular energy. Oral consumption of creatine increases and saturates the muscle content of creatine(1). Creatine supplementation is used to enhance athletic performance and build lean muscle mass. Numerous studies have reported that, when combined with a resistance training program, creatine can enhance the gains in fat free mass and lean body mass to a degree that is significantly greater than would be associated with training alone (2-12). This is likely due to Creatine’s ability to cause cells to swell, via an increase in intracellular volume (6, 13), which is believe to be an anabolic signal to promote protein synthesis(14). Also, Creatine enhances the resynthesis of the cells energy source, Adenosine Triphosphate (ATP). This can enable a higher training intensity to be maintained, which may ultimately lead to a greater stimulus for muscle growth (15).
Glutamine: Like Creatine, Glutamine is also found in skeletal muscle. The functions of Glutamine in the body include acid-base balance, nitrogen supply and protein synthesis. Glutamine is commonly used as a supplement to improve muscle function, decrease fatigue and improve recovery in exercising athletes (16). In human research, strenuous exercise decreased plasma levels of glutamine (17), and glutamine supplementation promoted storage of muscle glycogen following exercise (18). Furthermore, the provision of supplementary glutamine may spare muscle protein in the case of inadequate dietary intake and increase the cellular hydration status (20), which may be an anabolic signal (21). Glutamine’s role in immune support for exercising individuals has also been researched (19) and it is commonly used, in combination with protein, to increase muscle growth and improve immunity in well-trained individuals.
Carbohydrates: The physiological and performance effects of carbohydrate supplementation on aerobic endurance exercise have been extensively studied. Research also suggests that resistance exercise can reduce muscle glycogen stores, leading to fatigue and strength loss(22). So whether you are doing endurance training or weights, ingestion of carbohydrates is important. Carbohydrate ingestion can help enhance muscle glycogen re-synthesis, decrease recovery time and enable an increase in training volume(23).
Protein Blend: Proteins can be broadly classified as either fast or slow depending on how quickly they are absorbed (24). Prior to and immediately following exercise it may be beneficial to ingest protein sources that are rapidly absorbed and provide the muscle with amino acids to stimulate protein synthesis. However, a slow protein source may be beneficial to ensure the maintenance of blood amino acids in the hours after exercise and to promote an anti-catabolic environment. NitroVol contains a protein blend designed to achieve both these benefits. The whey protein in NitroVol can be considered a fast protein source that is rapidly absorbed (25), while casein derived from the whole milk proteins can be considered a slow protein (24).
NitroVol is not only for Bodybuilders. NitroVol is formulated to have a marked anabolic effect, making it suitable for anyone wanting to increase their lean muscle mass. Obviously bodybuilders could benefit from the cell volumising and metabolic advantages that NitroVol may provide. However, the physiological benefits of NitroVol are not exclusively limited to the bodybuilder. In fact, gains in lean muscle mass could benefit athletes in a number of sports, such as those requiring strength and power. Therefore, although the physiological effects of NitroVol are of obvious benefit to the bodybuilder, they may also offer benefit to athletes in a number of other sports like rugby league, rugby union, aussie rules, crossfit, swimming, powerlifiting and mma fighting. Furthermore, NitroVol should not be considered a supplement exclusively for athletes. Fitness enthusiasts or even individuals beginning a training program may greatly accelerate their strength, muscle gains and athletic performance by consuming NitroVol.
The combination of ingredients in NitroVol makes it a ready made and convenient stack to use. The ingredients have been selected to work synergistically and promote a range of benefits that are not able to be obtained via the ingestion of these ingredients individually. This means that NitroVol may offer benefits that cannot be obtained by simply consuming creatine, protein or glutamine individually.
NitroVol is best consumed immediately after training for several reasons. Research has shown that the ingestion of carbohydrate and essential amino acids immediately after training can further stimulate protein synthesis, above that of resistance training alone (26). The retention of creatine may also be greater if ingested immediate after muscular exercise (1). Furthermore, intense exercise can deplete plasma glutamine levels and it has been suggested that glutamine supplementation post exercise may restore physiological levels (19). Finally, exercise can deplete muscle glycogen stores, so it makes sense to ingest carbohydrates post exercise to replenish used glycogen (23).
The term ‘cell volumising’ has become popular terminology to describe the hydration status of a cell. It has become a talking point in sports nutrition circles as it appears that increasing cell volume may increase protein synthesis and reduce protein breakdown (14). Consequently, using supplements that increase skeletal muscle cellular hydration, or prevent declines in cellular volume, may optimise protein synthesis. NitroVol contains creatine and glutamine, which are both suggested to have cell volumising effects (6, 20).
Injuries are an unfortunate fact of life. However, with advances in modern medicine treatment, the rehabilitation of injuries has come along way. With many injuries, loss of muscle mass and strength occurs as a result of the immobilization required during the recovery period. This lost muscle mass and strength must be regained during the rehabilitation process. Research suggests Creatine may help reduce loss in muscle mass and strength during immobilization (28). As a great source of Creatine, plus other cell volumizing agents that stimulate protein synthesis, Nitrovol Lean Muscle may also benefit athletes needing to regain muscle mass and strength following an injury.
NitroVol is used by many elite teams and elite athletes and has not been reported to have any side effects. Furthermore, the key ingredients in NitroVol are reportedly well tolerated in human studies (27, 20, 25).
NitroVol Lean Muscle contains nothing on the WADA prohbitied substances list, and is certified by HASTA™. All supplements that bear this logo have been tested and certified as negative by a screen of over 200 WADA prohibited substances and are made to the highest quality per the GMP HACCP manufacturing guidelines. Therefore, NitroVol can be considered a safe and legal method of supplementing the diet, even for elite athletes subjected to regular drug testing. Designed with research, this post-workout supplement will take your workouts to the next level.
Nitrovol Lean Muscle has been designed to maximize fat free muscle mass, strength and power and aid recovery. It is perfect for building lean muscle mass and avoiding gains in body fat. Suitable for bodybuilders, athletes, sports players, fitness enthusiasts and even individuals beginning a training program, it compliments any training and strengthening regime and has a recommended dose of 1 x 60g serve per day.
(1) Harris, R. C., Soderlund, K., and Hultman, E. Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation. Clin Sci.(Lond) 1992;83(3):367-374.
(2) Arciero, P. J., Hannibal, N. S., III, Nindl, B. C., Gentile, C. L., Hamed, J., and Vukovich, M. D. Comparison of creatine ingestion and resistance training on energy expenditure and limb blood flow. Metabolism 2001;50(12):1429-1434.
(3) Jowko, E., Ostaszewski, P., Jank, M., Sacharuk, J., Zieniewicz, A., Wilczak, J., and Nissen, S. Creatine and beta-hydroxy-beta-methylbutyrate (HMB) additively increase lean body mass and muscle strength during a weight-training program. Nutrition 2001;17(7-8):558-566
(4) Becque, M. D., Lochmann, J. D., and Melrose, D. R. Effects of oral creatine supplementation on muscular strength and body composition. Med Sci.Sports Exerc. 2000;32(3):654-658
(5) Urbanski, R. L., Vincent, W. J., and Yaspelkis, B. B., III. Creatine supplementation differentially affects maximal isometric strength and time to fatigue in large and small muscle groups. Int J Sport Nutr. 1999;9(2):136-145.
(6) Bemben, M. G., Bemben, D. A., Loftiss, D. D., and Knehans, A. W. Creatine supplementation during resistance training in college football athletes. Med Sci.Sports Exerc. 2001;33(10):1667-1673
(7) Francaux, M. and Poortmans, J. R. Effects of training and creatine supplement on muscle strength and body mass. Eur.J Appl.Physiol Occup.Physiol 1999;80(2):165-168
(8) Mihic, S., MacDonald, J. R., McKenzie, S., and Tarnopolsky, M. A. Acute creatine loading increases fat-free mass, but does not affect blood pressure, plasma creatinine, or CK activity in men and women. Med Sci.Sports Exerc. 2000;32(2):291-296
(9) Maganaris, C. N. and Maughan, R. J. Creatine supplementation enhances maximum voluntary isometric force and endurance capacity in resistance trained men. Acta Physiol Scand. 1998;163(3):279-287
(10) Kirksey KB, Warren BJ, Stone MH, and et al. The effects of six weeks of creatine monohydrate supplementation in male and female track athletes. Med Sci Sports Exerc 1997;29(5 Suppl):S145.
(11) Greenhaff PL, Bodin K, Harris RC, and et al. The influence of oral creatine supplementation on muscle phosphocreatine resynthesis following intense contraction in man. J Physiol 1993;467:75p.
(12) Mihic S, MacDonald JR, McKenzie S, and et al. The effect of creatine supplementation on blood pressure, plasma creatine kinase, and body composition. FASEB J 1998;12:A652.
(13) Saab, G., Marsh, G. D., Casselman, M. A., and Thompson, R. T. Changes in human muscle transverse relaxation following short-term creatine supplementation. Exp.Physiol 2002;87(3):383-389.
(14) Häussinger D; Control of protein turnover by the cellular hydratation state; Ital J Gastroenterol. 1993 Jan; 25(1):42-8.
(15) Volek JS, Duncan ND, Mazzetti SA, Staron RS, Putukian M, Gomez AL, Pearson DR, Fink WJ, Kraemer WJ. Performance and muscle fiber adaptations to creatine supplementation and heavy resistance training. Med Sci Sports Exerc. 1999;31:1147–1156.
(16) Ohtani, M., Sugita, M., and Maruyama, K. Amino acid mixture improves training efficiency in athletes. J Nutr. 2006;136(2):538S-543S
(17) Kargotich, S., Rowbottom, D. G., Keast, D., Goodman, C., Dawson, B., and Morton, A. R. Plasma glutamine changes after high-intensity exercise in elite male swimmers. Res.Sports Med 2005;13(1):7-21
(18) Bowtell, J. L., Gelly, K., Jackman, M. L., Patel, A., Simeoni, M., and Rennie, M. J. Effect of oral glutamine on whole body carbohydrate storage during recovery from exhaustive exercise. J.Appl.Physiol 1999;86(6):1770-1777
(19) Castell, L.M., Poortmans, J.R. and Newsholme, E.A. Does glutamine have a role in reducing infections in athletes? European journal of applied physiology and occupational physiology 73: 488-490, 1996
(20) Antonio, J. and Street, C. Glutamine: a potentially useful supplement for athletes. Canadian journal of applied physiology. 24:1-14, 1999.
(21) Haussinger, D., Roth, E., Lang, F. and Gerok W. Cellular hydration state: an important determinant of protein catabolism in health and disease. Lancet. 341:1330-2, 1993
(22) Conley, M.S., Stone, M.H. Carbohydrate ingestion/supplementation for resistance exercise and training. Sports medicine 21:7-17, 1996.
(23) Haff, G.G., Lehmkuhl, M.J., McCoy, L.B. and Stone, M.H. Carbohydrate supplementation and resistance training. [Article] Journal of strength and conditioning research 17(1), 187-196, 2003.
(24) Boirie, Y., Dangin, M., Gachon, P., Vasson, M.P., Maubois, J.L. and Beaufrere, B. Slow and fast dietary proteins differently modulate postprandial protein accretion. Proceedings of the National Academy of Sciences of the United States of America. 94:14930-14935, 1997.
(25) Ha, E. Zemel, M.B. Functional properties of whey, whey components, and essential amino acids: mechanisms underlying health benefits for active people. Journal of Nutritional Biochemistry. 14:251-258, 2003
(26) Tipton, K.D., Rasmussen, B.B., Miller, S.L., Wolf, S.E., Owens-Stoval,l S.K., Petrini, B.E. and Wolfe, R.R. Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise. American Journal of Physiology - Endocrinology & Metabolism. 281:E197-E206, 2001
(27) Schilling, B.K., Stone, M.H., Utter, A., Kearney, J.T., Johnson, M., Coglianese, R., Smith, L., O'Bryant, H.S., Fry, A.C., Starks, M., Keith, R. and Stone, M.E. Creatine supplementation and health variables: a retrospective study. Medicine and science in sports and exercise. 33:183-188, 2001
(28) Johnston AP et al; Effect of creatine supplementation during cast-induced immobilization on the preservation of muscle mass, strength, and endurance ; J Strength Cond Res. 2009 Jan;23(1):116-20..