Melibol Questions and Answers
Melibol Q&A
Q1: How is Melibol Formulated?
Melibol is a combination of Branched-chain amino acids [leucine, isoleucine,
and valine], glutamine, magnesium & manganese.
Among its numerous ingredients the BCAAs are essential for numerous physiological
processes in the human body. They are needed for the maintenance of muscle tissue
and appear to preserve muscle glycogen stores1 and help prevent muscle protein
breakdown during exercise.2
They are needed for the maintenance of muscle tissue and appear to preserve
muscle glycogen stores1 and help prevent muscle protein breakdown during exercise.2
Q2: Is Melibol only for elite athletes?
No, if you undertake physical exercise, research has shown that BCAA supplementation
(typically 10-20 grams per day) may be useful in prolonging endurance performance
in the heat.11 Studies by one group of researchers suggest's that BCAA supplementation
may also improve exercise-induced declines in some aspects of mental functioning.345
Q3. Are the essential branched chain amino acids (BCAA's) of special
importance for athletes ?
Yes, because BCAA's are metabolised in the muscle, rather than in the liver.
After digestion once protein is broken down into individual amino acids these
aminos can either be used to build new proteins or be burned as fuel to produce
energy. During exercise, depending on your training, you will ideally burn mostly
fat and stored carbohydrate (glycogen) as fuel but eventually your body will
also turn to protein, particularly the BCAAs, as glycogen becomes depleted.
Q4. Why should an athlete utilise BCAA's?
Simply because BCAA's are released from the liver into circulation enabling
skeletal muscles to break down the BCAA's for energy. During recovery when other
fuel sources are available [such as carbohydrates and fats] BCAA's are used
in protein synthesis. This is what an athlete requires for muscle building.
BCAA's represent over 50% of the total amino acids released into general circulation
to be taken up by the muscles.
Q5. Will BCAA's assist recovery?
Yes, the greatest benefit to training athletes is the increase in metabolic
efficiency or recovery that follows supplementation. Many athletes introducing
Melibol to their current supplement stack claim to feel a substantial decrease
in the amount of post exercise muscle soreness soon after beginning this BCAA
supplementation..Increased recovery enables more frequent training. Intense
athletic training can affect the immune system, research on BCAA's has been
reported to restore depleted glutamine stores and immune factors in elite athletes,
and led to a reported one-third fewer symptoms of infection during the period
of supplementation.8
Q5. Are BCAA's backed by research?
A good deal of research has been done on branched-chain amino acids (BCAAs)
in athletes, but results are quite mixed.
Q3: How much BCAA is usually taken?
Most sedentary diets provide an adequate amount of BCAA's which is about 55-143
mg per kg of body weight 6 7 , however athletes involved in intense training
often take 5 grams of leucine, 4 grams of valine, and 2 grams of isoleucine
per day to prevent muscle loss and increase muscle gain, though most research
does not support this use of BCAAs.
Q5: Why does Melibol recommend a serving size of 2 gm per day?
The daily consumption is based on the belief that most athletic individuals
are already consuming protein rich whole foods and a protein supplement.
Q6: Are there any side effects or interactions?
Side effects have not been reported with the use of BCAAs. At high intakes,
BCAAs are converted into other amino acids, used as energy, or converted to
fat for storage.
However, individuals with kidney or liver disease should not consume high intakes
of amino acids without consulting their doctor. At the time of writing, there
were no well-known drug interactions with branched-chain amino acids.
References:
1. Blomstrand E, Ek S, Newsholme EA. Influence of ingesting a solution of branched-chain
amino acids on plasma and muscle concentrations of amino acids during prolonged
submaximal exercise. Nutrition 1996;12:485-90.
2. MacLean DA, Graham TE, Satlin B. Branched-chain amino acids augment ammonia
metabolism while attenuating protein breakdown during exercise. Am J Physiol
1994;267:E1010-
3. Hassmén P, Blomstrand E, Ekblom B, Newshomle EA. Branched-chain amino
acid supplementation during 30-km competitive run: mood and cognitive performance.
Nutrition 1994;10:405-10.
4. Blomstrand E, Hassmen P, Ek S, et al. Influence of ingesting a solution of
branched-chain amino acids on perceived exertion during exercise. Acta Physiol
Scand 1997;159:41-49.
5. Blomstrand E, Hassmen P, Ekblom B, et al. Administration of branched-chain
amino acids during sustained exercise-effects on performance and on plasma concentration
of some amino acids. Eur J Appl Physiol 1991;63:83-88.
6. Zello GA, Wykes LF, Ball RO, et al. Recent advances in methods of assessing
dietary amino acid requirements for adult humans. J Nutr 1995;125:2907-15.
7. Young VR, Bier DM, Pellett PL. A theoretical basis for increasing current
estimates of the amino acid requirements in adult man, with experimental support.
Am J Clin Nutr 1989;50:80-92.
8. Bassit RA, Sawada LA, Bacurau RF, et al. The effect of BCAA supplementation
upon the immune response of triathletes. Med Sci Sports Exerc 2000;32:1214-9.
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